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accession-icon GSE54886
Susceptibility to photo-oxidative damage of mice lacking the Rod derived Cone Viability Factor gene Nxnl1
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon

Description

Rod-derived Cone Viability Factor is a trophic factor of the thioredoxins family that promotes the survival of cone photoreceptors. It is encoded by the nucleoredoxin-like gene 1 Nxnl1 which also encodes by alternative splicing for RdCVFL, for a thioredoxin enzyme that interacts with the protein TAU. The role of thioredoxins in the defense mechanism against oxidation led us to examine the retinal phenotype of the Nxnl1-/- mouse after photo-oxidative stress.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE9098
Estrogen-modulated gene expression in c-kit+ stem cells and CD44+ stromal cells
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon

Description

The recent interest in the role of bone marrow derived endothelial progenitor cells in the benefits of estrogen on cardiovascular health brought us to evaluate if estrogen could affect cardiac repair more broadly by regulating biological processes involved in the functional organization of the bone marrow stem cell niche.

Publication Title

Estrogen-induced gene expression in bone marrow c-kit+ stem cells and stromal cells: identification of specific biological processes involved in the functional organization of the stem cell niche.

Sample Metadata Fields

Sex, Age

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accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
accession-icon GSE96849
SAGA Is a General Cofactor for RNA Polymerase II Transcription
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 68 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The SAGA co-activator has been implicated in the regulation of a smal subset of genes in budding yeast in transcriptomic analyses performed in steady-state levels of RNA.

Publication Title

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Sample Metadata Fields

Genetic information

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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