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accession-icon GSE13379
Application of a translational profiling approach for the comparative analysis of CNS cell types.
  • organism-icon Mus musculus
  • sample-icon 107 Downloadable Samples
  • Technology Badge Icon

Description

Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, Translating Ribosome Affinity Purification (TRAP), permits comprehensive studies of translated mRNAs in genetically defined cell populations following physiological perturbations.

Publication Title

Application of a translational profiling approach for the comparative analysis of CNS cell types.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE13394
A translational profiling approach for the molecular characterization of CNS cell types
  • organism-icon Mus musculus
  • sample-icon 35 Downloadable Samples
  • Technology Badge Icon

Description

The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE13387
Comparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons, Motor Neurons, and Purkinje Neurons
  • organism-icon Mus musculus
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon

Description

The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.

Publication Title

A translational profiling approach for the molecular characterization of CNS cell types.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE13386
Comparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons, cocaine treatment
  • organism-icon Mus musculus
  • sample-icon 19 Downloadable Samples
  • Technology Badge Icon

Description

The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE13385
Comparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons and whole brain
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon

Description

The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.

Publication Title

A translational profiling approach for the molecular characterization of CNS cell types.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE13384
Comparative analysis of Drd1+ Medium Spiny Neurons and Drd2+ Medium Spiny Neurons
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon

Description

The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.

Publication Title

A translational profiling approach for the molecular characterization of CNS cell types.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE16067
Gene expression analysis in control and HIF-2 alpha deficient murine lung endothelial cells under hypoxia
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon

Description

Journal : Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13.

Publication Title

Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis.

Sample Metadata Fields

Specimen part

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accession-icon GSE28736
BATF knockout B cells
  • organism-icon Mus musculus
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon

Description

compare wild type and Batf-/- B cells activated for 0 1 or 2 days in vitro.

Publication Title

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.

Sample Metadata Fields

Specimen part

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accession-icon GSE26809
FMRP Associates with Polyribosomes
  • organism-icon Mus musculus
  • sample-icon 26 Downloadable Samples
  • Technology Badge Icon

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE26745
Comparison of total and polyribosome-associated mRNA levels in male Fmr1 KO mice and male WT littermates
  • organism-icon Mus musculus
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon

Description

The Fragile X Mental Retardation Protein, FMRP, is thought to regulate the translation of a specific set of neuronal mRNAs on polyribosomes. Therefore, we prepared polyribosomes on sucrose gradients and purified mRNA specifically from these fractions, as well as the total mRNA levels, to determine whether a set of mRNAs might be changed in its % association with polyribosomes in the absence of FMRP in the KO mouse model.

Publication Title

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Sample Metadata Fields

Sex, Specimen part

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

Powered by Alex's Lemonade Stand Foundation

Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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