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accession-icon GSE6933
Unique Molecular Signature of Multipotent Adult Progenitor Cells (Affy)
  • organism-icon Mus musculus, Rattus norvegicus
  • sample-icon 1 Downloadable Sample
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Description

We compare the transcriptome of embryonic stem cells (ESCs), adult stem cells with apparent greater differentiation potential such as multipotent adult progenitor cells (MAPCs), mesenchymal stem cells (MSCs) and neurospheres (NS). Mouse and rat MAPCs were used in this study and two different array platforms (Affymetrix and NIA) were used for mouse samples.

Publication Title

Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE25640
Expression data from wild type or FIZZ2 knockout murine lungs
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
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Description

To study the possible fibrotic role of FIZZ2, bleomycin was used to induce pulmonary fibrosis in wild type and FIZZZ2 knockout mice, lungs were then harvested and processed for RNA isolation.

Publication Title

FIZZ2/RELM-β induction and role in pulmonary fibrosis.

Sample Metadata Fields

Specimen part

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accession-icon GSE17105
Gene expression regulated by G-actin switch
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
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Description

We analysed the G-actin regulated transcriptome by gene expression analysis using previously characterised actin binding drugs. We found many known MAL/MRTF-dependent target genes of serum response factor (SRF) as well as unknown directly regulated genes.

Publication Title

Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction.

Sample Metadata Fields

Time

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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