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accession-icon GSE23305
WT vs c-Maf KO fetal liver macrophage
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
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Description

Homozygous disruption of c-Maf led to embryonic lethality and impaired erythroblastic island formation. c-Maf is expressed in the fetal liver macrophages. It suggests that macrophages are responsible for the lethality of c-Maf knock-out embryos. To search downstream genes of c-Maf, we surveyed genes associated with macrophage function by microarray analysis.

Publication Title

c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver.

Sample Metadata Fields

Specimen part

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accession-icon GSE48595
Expression data analysis of murine pulmonary cryptococcosis induced by C. gattii
  • organism-icon Mus musculus
  • sample-icon 3 Downloadable Samples
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Description

Our previous investigation indicated that high-virulence C. gattii (C. gattii TIMM 4097) tend to reside in the alveoli, whereas low-virulence C. gattii (C. gattii TIMM 4903) tend to be washed out from the alveoli and move into the central side of the respiratory system. To test this hypothesis, we performed microarray assay.

Publication Title

How histopathology can contribute to an understanding of defense mechanisms against cryptococci.

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE91394
Expression data from brains of BCAS1 knockout or wildtype mice
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
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Description

We used microarrays to compare the expression profiles between brains of BCAS1 knockout and wild type mice

Publication Title

Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain.

Sample Metadata Fields

Sex, Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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