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accession-icon GSE35318
p38a-dependent gene expression in dendritic cells
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
  • Technology Badge Icon

Description

Gene expression in wild-type and p38a-knockout dendritic cells (DCs) were compared. Lymph node dendritic cells were isolated from mice, and left unstimulated and stimulated with Pam3CSK4, a toll-like receptor 2 agonist.

Publication Title

Cell type-specific targeting dissociates the therapeutic from the adverse effects of protein kinase inhibition in allergic skin disease.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE17760
Expression data from Ts1Cje and disomic C57BL/6 adult neurospheres
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon

Description

Down syndrome is the most common form of genetic mental retardation. How Trisomy 21 causes mental retardation remains unclear and its effects on adult neurogenesis have not been addressed. To gain insight into the mechanisms causing mental retardation we used microarrays to investigate gene expression differences between Ts1Cje (a mouse model of Down syndrome) and C57BL/6 littermate control neurospheres. The neurospheres were generated from neural stem cells and progenitors isolated from the lateral walls of the lateral ventricles from adult mice.

Publication Title

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.

Sample Metadata Fields

Sex, Disease

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accession-icon GSE87769
Identification of Tfcp2l1 target genes in the mouse kidney
  • organism-icon Mus musculus, Rattus norvegicus
  • sample-icon 6 Downloadable Samples
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Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Transcription factor <i>TFCP2L1</i> patterns cells in the mouse kidney collecting ducts.

Sample Metadata Fields

Specimen part

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accession-icon GSE85325
Tfcp2l1 controls cellular patterning of the collecting duct.
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon

Description

Gene expression analysis of mouse kidney after conditional inactivation of transcription factor Tfcp2l1

Publication Title

Transcription factor <i>TFCP2L1</i> patterns cells in the mouse kidney collecting ducts.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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