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accession-icon GSE108036
Comparative analysis of cartilage tissue from ANP32A knockout mice and wildtype C57/Bl6 mice
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
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Description

A genetic association between the ANP32A gene and osteoarthritis has been suggested. We compared transcriptome profiles of the articular cartilage and subchondral bone from mice deficient in ANP32A with wild-type mice to get insights into the role of ANP32A in the pathogenesis of ostearthritis.

Publication Title

ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE112776
Expression data for High and Low permeable brain metastases in 231-BR mouse model
  • organism-icon Mus musculus, Homo sapiens
  • sample-icon 22 Downloadable Samples
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Description

All highly and poorly permeable metastases from the same mouse brain were collected by laser capture microdissection. Total RNA from both metastatic lesions and immediate microenvironment was isolated from 5 mice bearing 231-BR metastases. As control 4 healthy mouse brains were included.

Publication Title

Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases.

Sample Metadata Fields

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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