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accession-icon GSE17497
Gene expression in murine acute lymphoblastic leukemia in vivo after allogeneic or syngeneic bone marrow transplantation
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
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Description

This study compared gene expression in murine bcr-abl positive acute lymphoblastic leukemia cells in vivo in allogeneic BMT recipients compared to syngneneic BMT recipients.

Publication Title

Differential gene expression in acute lymphoblastic leukemia cells surviving allogeneic transplant.

Sample Metadata Fields

Specimen part

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accession-icon GSE49237
Analysis of TBR1 downnstream target genes in embryonic forebrains
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
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Description

TBR1 is a forebrain specific T-box transcription factor. Tbr1-/- mice have been characterized by defective axonal projections from cerebral cortex and abnormal neuronal migration of cerebral cortex and amygdala.

Publication Title

Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE12982
Expression data from mouse ES cells and various differentiated cell types
  • organism-icon Mus musculus
  • sample-icon 53 Downloadable Samples
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Description

We used microarrays to detail the role of Polycomb proteins including Ezh2 and Eed in maintaining ES cell identity and executing pluripotency.

Publication Title

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE10784
Gene profile data from Df(16)A/+ and wild type littermates
  • organism-icon Mus musculus
  • sample-icon 40 Downloadable Samples
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Description

This represents an unbiased evaluation of the transcriptional response in the prefrontal cortex and hippocampus areas in the Df(16)A/+ mice, a mouse model of human 22q11 microdeletion syndrome. These mice were generated by chromosomal engineering and carry a microdeltion of ~1.3Mb in the mouse locus syntenic to the human 22q11.1

Publication Title

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE40605
Histone Demethylase Lsd1 Represses Hematopoietic Stem and Progenitor Cell Signatures During Blood Cell Maturation.
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation.

Sample Metadata Fields

Sex, Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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