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accession-icon GSE9460
Mouse model of Osteosarcoma
  • organism-icon Mus musculus
  • sample-icon 21 Downloadable Samples
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Description

expression analysis from a genetically engineered mouse model of osteosarcoma

Publication Title

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE10908
Differential gene expression in ADAM10 over-expressing transgenic mice
  • organism-icon Mus musculus
  • sample-icon 27 Downloadable Samples
  • Technology Badge Icon

Description

In a transgenic mouse model of Alzheimer disease (AD), cleavage of the amyloid precursor protein (APP) by the -secretase ADAM10 prevented amyloid plaque formation and alleviated cognitive deficits. Furthermore, there was a positive influence of ADAM10 over-expression on neurotransmitter-specific formation of synapses and on synaptic plasticity.

Publication Title

Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.

Sample Metadata Fields

Sex, Age

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