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accession-icon GSE62385
Intermittent Hypoxia ageing
  • organism-icon Mus musculus
  • sample-icon 18 Downloadable Samples
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Description

Expression data from mice exposed to intermittent hypoxia and mice reared for 12 months. We used microarrays to analyze the transcriptome of hippocampus from mice exposed to intermittent hypoxia or aged mice.

Publication Title

Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE43970
Reconstruction of the dynamic regulatory network that controls Th17 cell differentiation by systematic perturbation in primary cells
  • organism-icon Mus musculus
  • sample-icon 86 Downloadable Samples
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Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Dynamic regulatory network controlling TH17 cell differentiation.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE85171
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition
  • organism-icon Mus musculus, Homo sapiens
  • sample-icon 4 Downloadable Samples
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Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.

Sample Metadata Fields

Treatment, Time

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accession-icon GSE85168
Oncogenic RAS blocks myogenic differentiation
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon

Description

C2C12 mouse myoblasts expressing RAS mutants identified in human tumors fail to differentiate in low serum media.

Publication Title

MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.

Sample Metadata Fields

No sample metadata fields

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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